Scholar's profile
Chan, Michael Wing Yan
Chan, Michael Wing Yan
Professor
Department of Biomedical Sciences
biowyc@ccu.edu.tw
Visit my personal website

Scopus Data (view scopus profile)

Publication Achievements 1998 - 2025
Publication Index
Documents
153
CITATIONS
6981
H-INDEX
42
FWCI
1.11
Co-authors
666
Last Sync Date: 2025-08-17

Google Scolar

ORCID

Overview Research output International exchange activities
Research output per year
1998
2025
129
Article
4
Book Chapter
5
Editorial
2
Erratum
1
Letter
8
Review
2
Short Survey

Scopus

Print-friendly
A total of 129 data records, Page 1 / 13 , records per page, Go to page  
1 2 3 4 5 6 7 8 9 ... 13

Publication

Print-friendly
  • 1 Reactivation of SYTL3 reshapes the anti-tumor immune microenvironment in gastric cancer 
    Low JT; Chan MW
    The 83nd Annual Meeting of the Japanese Cancer Association 2024 / 9
    Seminar Paper
  • 2 Detection of heart-specific methylated CpG sites from cfDNA as a biomarker for Doxorubicin-induced cardiotoxicity
    Hsu PY; Lee YY; Huang WH; Passier R; Lee SJ; Hong CL; Hong SK; Lin HY; Lin CH; Lee YA; Desaubry L; Nebigil CG; Chan MWY
    The 83nd Annual Meeting of the Japanese Cancer Association 2024 / 9
    Seminar Paper
  • 3 Unraveling the role of DNA/RNA sensing pathways induced by LINE-1 hypomethylation in doxorubicin-mediated cardiotoxicity
    Lee YY; Hsu PY; Huang WH; Passier R; Desaubry L; Nebigil CG; and Chan MWY
    The 83nd Annual Meeting of the Japanese Cancer Association 2024 / 9
    Seminar Paper
  • 4 ARID1A depletion enhances immune checkpoint blockade in bladder cancer
    Kung C; Tsai LHJ; Hsu A; Chan MWY
    The 83nd Annual Meeting of the Japanese Cancer Association 2024 / 9
    Seminar Paper
  • 5 A E2F6 ceRNA network suppresses dendritic cell function, via PBX1/IL-10 signaling, in ovarian cancer
    Chan MWY; Chen YC; Lin CW; Cheng F; Yan CCS; Hsu CP; Chuang YM; Low JT; Ma X; Haung YT; Chang CB; Li C; Lai HC; Wu SF; Hung SH; Tsai JC
    American Association for Cancer Research (AACR) Annual Meeting 2024 2024 / 4
    Seminar Paper
  • 6 Immunological Hide-and-Seek: Epigenetically Reprogrammed Cancer Cells and the Dynamics of CD8+ T Cells
    Low JT; Chan MW; Shen CH; Wei KL
    Molecular Biology Reports 2024 / 9
    Journal Article
  • 7 FOXP4 Is a Direct YAP1 Target That Promotes Gastric Cancer Stemness and Drives Metastasis
    Liu X; Chen B; Xie F; Wong KY; Cheung AH; Zhang J; Wu Q; Fang C; Hu J; Wang S; Xu D; Chen J; Wang Y; Wong CC; Chen H; Wu WKK; Yu J; Chan MWY; Tsang CM; Lo KW; Tse GMK; To KF; Kang W
    Cancer Research 2024 / 11
    Journal Article
  • 8 Epigenetic reprogramming of SYTL3 restores an inflamed tumor microenvironment in gastric cancer
    Low JT; Chan MW
    The 82nd Annual Meeting of the Japanese Cancer Association 2023 / 9
    Seminar Paper
  • 9 Acetyl-CoA distribution devotes STAT3 related neuronal methylation phenotype and pro-inflammatory niche in gastric cancer
    Chan MW
    Gordon Research Conference on Cancer Genetics and Epigenetics 2023 / 5
    Seminar Paper
  • 10 Cyproheptadine exhibits antitumor activity by reversing the epigenetic silencing of IRF6 in urothelial carcinoma 
    Chen PC; Lin GL; Lin HY; Huang WH; Chuang YM; Lin RI; Wu SF; Shen CH; Chan MWY
    American Association for Cancer Research (AACR) Annual Meeting 2023 2023 / 4
    Seminar Paper
1 2 3 4 5 6

Projects

Print-friendly
Teacher's name Research Units Year Project title Project position Commissioning unit Implementation period
Chan, Michael Wing Yan Department of Biomedical Sciences 2026 SYTL3在逆轉泌尿道上皮癌腫瘤免疫逃避作用的研究（3/3） PI 國家科學及技術委員會 2026/08/01-2027/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2025 探索腫瘤微環境中活化態胰臟星狀細胞旁分泌信號的傳導與腫瘤免疫學的作用（3/3） Co-PI 國家科學及技術委員會 2025/08/01-2026/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2025 SYTL3在逆轉泌尿道上皮癌腫瘤免疫逃避作用的研究（2/3） PI 國家科學及技術委員會 2025/08/01-2027/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2025 114年全球優秀青年學子來臺蹲點計畫(TEEP)_生源型_陳永恩老師 PI 教育部 2025/01/01-2025/12/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2025 博士級研究人員周志傑-「SYTL3在逆轉泌尿道上皮癌腫瘤免疫逃避作用的研究」(研發替代役) PI 國家科學及技術委員會 2025/06/19-2026/06/18
Chan, Michael Wing Yan Department of Biomedical Sciences 2024 探討副流感嗜血桿菌誘導的先天免疫耐受性及其作用機制 Co-PI 國家科學及技術委員會 2024/08/01-2025/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2024 探討谷氨酸轉運蛋白SLC25A22在胃癌進展中的功能作用 PI 思凱生科有限公司 2024/12/01-2025/11/30
Chan, Michael Wing Yan Department of Biomedical Sciences 2024 探索腫瘤微環境中活化態胰臟星狀細胞旁分泌信號的傳導與腫瘤免疫學的作用（2/3） Co-PI 國家科學及技術委員會 2024/08/01-2026/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2024 教育部補助大學校院產學合作培育博士級研發人才計畫-跨領域科學國際博士學位學程產學組(113學年度) PI 教育部 2024/08/01-2025/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2024 SYTL3在逆轉泌尿道上皮癌腫瘤免疫逃避作用的研究（1/3） PI 國家科學及技術委員會 2024/08/01-2027/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2024 臺法(FR)雙邊協議型擴充加值(add-on) 國際合作研究計畫-HDAC, eIF4A, 及prohibitins 之三重抑制對抗泌尿道上皮癌的研究（3/3） PI 國科會 2024/01/01-2024/12/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2024 跨領域醫療議題(六)-ARID1A 對免疫檢查點阻斷劑在順鉑引導治療後之膀胱癌中的作用研究 PI 戴德森醫療財團法人嘉義基督教醫院 2024/01/01-2024/12/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2024 113大專生計畫-LINE-1 hypomethylation triggers DNA/RNA sensing pathways in doxorubicin-induced cardiotoxicity PI 國科會 2024/07/01-2025/02/28
Chan, Michael Wing Yan Department of Biomedical Sciences 2024 可應用於癌症與生殖醫學之AI智慧型快速多重檢測光學式生物晶片-可應用於癌症與生殖醫學之AI智慧型快速多重檢測光學式生物晶片(1/5) Co-PI 國家科學及技術委員會 2024/07/01-2025/06/30
Chan, Michael Wing Yan Department of Biomedical Sciences 2024 嘉基配合款113學年-大學校院產學合作培育博士級研發人才計畫 PI 戴德森醫療財團法人嘉義基督教醫院 2024/08/01-2024/12/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2023 佩你安透過抑制脂質代謝恢復泌尿道上皮癌抗腫瘤免疫反應之研究（3/3） PI 國科會 2023/08/01-2024/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2023 臺法(FR)雙邊協議型擴充加值(add-on) 國際合作研究計畫-HDAC, eIF4A, 及prohibitins 之三重抑制對抗泌尿道上皮癌的研究（2/3） PI 國科會 2023/01/01-2024/12/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2023 112年度健全發展計畫-跨域教學實踐場域-理學院-地環系 PI 教育部 2023/12/15-2024/12/14
Chan, Michael Wing Yan Department of Biomedical Sciences 2023 112年度健全發展計畫-跨域教學實踐場域-理學院-物理系 PI 教育部 2023/12/15-2024/12/14
Chan, Michael Wing Yan Department of Biomedical Sciences 2023 112年度健全發展計畫-跨域教學實踐場域-理學院-化生系 PI 教育部 2023/12/15-2024/12/14
Chan, Michael Wing Yan Department of Biomedical Sciences 2023 應用奈米光電結構提升上轉換螢光強度之研究(3/3) Co-PI 國家科學及技術委員會 2023/08/01-2025/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2023 112-113年「全球優秀青年學子來臺蹲點計畫(TEEP)」生源型_陳永恩老師 PI 教育部 2023/12/01-2025/12/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2023 大林慈濟跨領域醫療(一)-表觀遺傳藥物在膀胱癌中逆轉腫瘤免疫逃脫之研究 PI 佛教慈濟醫療財團法人大林慈濟醫院 2023/02/01-2025/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2023 探索腫瘤微環境中活化態胰臟星狀細胞旁分泌信號的傳導與腫瘤免疫學的作用（1/3） Co-PI 國家科學及技術委員會 2023/08/01-2026/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2022 臺法(FR)雙邊協議型擴充加值(add-on) 國際合作研究計畫-HDAC, eIF4A, 及prohibitins 之三重抑制對抗泌尿道上皮癌的研究（1/3） PI 國科會 2022/01/01-2024/12/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2022 科技部補助生物醫學科學系陳永恩教授12/2-12/3舉辦「第四屆臺灣表基因體學研討會及生物科技暨健康產業國際學術研討會」 PI 國科會 2022/07/01-2023/01/03
Chan, Michael Wing Yan Department of Biomedical Sciences 2022 佩你安透過抑制脂質代謝增加泌尿道上皮癌抗腫瘤免疫反應之研究 PI 思凱生科有限公司 2022/01/01-2023/12/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2022 111大專生研究計畫-The strategy of enhancing efficacy of immune checkpoint blockade in ARID1A-deficient bladder cancer PI 國科會 2022/07/01-2023/02/28
Chan, Michael Wing Yan Department of Biomedical Sciences 2022 應用奈米光電結構提升上轉換螢光強度之研究(2/3) Co-PI 國科會 2022/08/01-2023/11/30
Chan, Michael Wing Yan Department of Biomedical Sciences 2022 佩你安透過抑制脂質代謝恢復泌尿道上皮癌抗腫瘤免疫反應之研究（2/3） PI 國科會 2022/08/01-2024/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2021 博士級研究人員林冠伶-佩你安透過抑制脂質代謝恢復泌尿道上皮癌抗腫瘤免疫反應之研究 PI 國科會 2021/08/01-2022/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2021 佩你安透過抑制脂質代謝恢復泌尿道上皮癌抗腫瘤免疫反應之研究（1/3） PI 國科會 2021/08/01-2024/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2021 智慧化奈米生物感測儀及其應用(3/3) Co-PI 國科會 2021/08/01-2022/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2021 110大專生計畫- The role of SYTL3 in enhancing sensitivity of immune checkpoint inhibitor in bladder cancer. PI 國科會 2021/07/01-2022/02/28
Chan, Michael Wing Yan Department of Biomedical Sciences 2021 應用奈米光電結構提升上轉換螢光強度之研究(1/3) Co-PI 國科會 2021/08/01-2022/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2021 博士級研究人員林冠伶-佩你安於泌尿道上皮癌作為表觀遺傳修飾藥物以增加免疫治療之研究 PI 國科會 2021/01/01-2021/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2020 佩你安於泌尿道上皮癌作為表觀遺傳修飾藥物以增加免疫治療之研究(2/2) PI 國科會 2020/08/01-2021/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2020 智慧化奈米生物感測儀及其應用(2/3) Co-PI 國科會 2020/08/01-2021/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2020 臺法(FR)國合計畫-建基於共振波導光柵之高靈敏度廣視野光學顯微術(3/3) Co-PI 國科會 2020/01/01-2021/12/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2020 稀土上轉換螢光奈米粒子於奈米尺度溫度感測、螢光影像、生化檢測、及光熱療法之應用（3/3） Co-PI 國科會 2020/08/01-2021/10/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2019 (陳建易)108-109年優秀外國青年來臺蹲點計畫-12月核定(整合型) SI 教育部 2019/12/03-2023/12/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2019 臺歐盟國合計畫-早期偵測及預防因癌症化療引發心臟功能受損及心衰竭(3/3) PI 國科會 2019/05/01-2021/09/30
Chan, Michael Wing Yan Department of Biomedical Sciences 2019 智慧化奈米生物感測儀及其應用(1/3) Co-PI 國科會 2019/08/01-2020/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2019 佩你安於泌尿道上皮癌作為表觀遺傳修飾藥物以增加免疫治療之研究(1/2) PI 國科會 2019/08/01-2021/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2019 臺法(FR)國合計畫-建基於共振波導光柵之高靈敏度廣視野光學顯微術(2/3) Co-PI 國科會 2019/01/01-2021/12/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2019 環境塑化劑導致小兒過敏性疾病增加之跨代效應與表基因機制研究-塑化劑鄰苯二甲酸二(2-乙基己基)酯於哺乳動物細胞之異常表基因機轉(3/3) PI 國科會 2019/08/01-2020/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2019 稀土上轉換螢光奈米粒子於奈米尺度溫度感測、螢光影像、生化檢測、及光熱療法之應用（2/3） Co-PI 國科會 2019/08/01-2021/10/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2018 環境塑化劑導致小兒過敏性疾病增加之跨代效應與表基因機制研究-塑化劑鄰苯二甲酸二(2-乙基己基)酯於哺乳動物細胞之異常表基因機轉(2/3) PI 國科會 2018/08/01-2019/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2018 高齡醫療議題研究 Co-PI 戴德森醫療財團法人嘉義基督教醫院 2018/12/03-2020/06/30
Chan, Michael Wing Yan Department of Biomedical Sciences 2018 臺法(FR)國合計畫-建基於共振波導光柵之高靈敏度廣視野光學顯微術(1/3) Co-PI 國科會 2018/01/01-2021/12/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2018 RCN009-Cell free DNA ---應用於高齡社區乳癌之偵測 PI 戴德森醫療財團法人嘉義基督教醫院 2018/12/03-2020/06/30
Chan, Michael Wing Yan Department of Biomedical Sciences 2018 臺歐盟國合計畫-早期偵測及預防因癌症化療引發心臟功能受損及心衰竭(2/3) PI 國科會 2018/05/01-2021/09/30
Chan, Michael Wing Yan Department of Biomedical Sciences 2018 稀土上轉換螢光奈米粒子於奈米尺度溫度感測、螢光影像、生化檢測、及光熱療法之應用（1/3） Co-PI 國科會 2018/08/01-2021/10/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2018 107大專生計畫-miR-193a於小鼠膀胱癌細胞中對PBX1之表基因調節與免疫逃避的關聯性 PI 國科會 2018/07/01-2019/02/28
Chan, Michael Wing Yan Department of Biomedical Sciences 2017 106大專生計畫-Global epigenomic analysis to investigate the role of JAK/STAT signaling in gastric carcinogenesis PI 國科會 2017/07/01-2018/02/28
Chan, Michael Wing Yan Department of Biomedical Sciences 2017 科技部生命科學研究推動中心補助生命科學系陳永恩教授於106年03月17日至106年03月18日舉辦「第三屆台灣表基因體學及系統生物學國際研討會」 PI 國科會 2017/03/01-2017/03/18
Chan, Michael Wing Yan Department of Biomedical Sciences 2017 環境塑化劑導致小兒過敏性疾病增加之跨代效應與表基因機制研究-塑化劑鄰苯二甲酸二(2-乙基己基)酯於哺乳動物細胞之異常表基因機轉(1/3) PI 國科會 2017/08/01-2018/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2017 Cyproheptadine抑制膀胱癌的效果與機轉之探討(3/3) PI 國科會 2017/08/01-2018/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2017 臺歐盟國合計畫-早期偵測及預防因癌症化療引發心臟功能受損及心衰竭(1/3) PI 國科會 2017/05/01-2021/09/30
Chan, Michael Wing Yan Department of Biomedical Sciences 2017 科技部補助生命科學系陳永恩教授於106年03月17日至106年03月18日舉辦「第三屆台灣表基因體學及系統生物學國際研討會」 PI 國科會 2017/03/01-2017/03/18
Chan, Michael Wing Yan Department of Biomedical Sciences 2016 Cyproheptadine抑制膀胱癌的效果與機轉之探討(2/3) PI 國科會 2016/08/01-2018/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2015 Cyproheptadine抑制膀胱癌的效果與機轉之探討(1/3) PI 國科會 2015/08/01-2018/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2015 探討去甲基化藥物(5-Aza-2'-deoxycytidine)在實驗性自體免疫腦脊髓炎小鼠的保護機制 Co-PI 國科會 2015/08/01-2016/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2015 miR-193a 之雙重表基因調控及其在卵巢癌之臨床應用研究 PI 國科會 2015/08/01-2016/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2014 EZH2在卵巢癌中作為TGF-beta標的基因之表基因開關以調控上皮-間質細胞轉換(EMT)之角色及其在癌症治療之應用研究 PI 國科會 2014/08/01-2015/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2013 大專生計畫-Tet1對於調控卵巢癌細胞株表基因之角色 PI 國科會 2013/07/01-2014/02/28
Chan, Michael Wing Yan Department of Biomedical Sciences 2013 以實驗性自體免疫腦脊髓膜炎探討去甲基化藥劑 (5-AZA-2-deoxycytidine) 促使Foxp3基因表現及其免疫調控機制 Co-PI 國科會 2013/08/01-2014/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2013 TGF-beta 調控之腫瘤抑制miR-193a在卵巢癌中之雙重表基因變異及其在癌症治療上之轉譯應用研究 PI 國科會 2013/08/01-2014/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2012 TGF-beta/SMAD 訊息傳遞路徑對其標的基因之表基因變異以調控上皮-間質轉換(EMT)之角色及其在卵巢癌之標靶治療之轉譯應用研究 PI 國科會 2012/08/01-2013/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2012 建構偵測污染食品微生物的微型化全分析快速篩檢平台—以沙門氏菌檢測為例-總計畫暨子計畫一：功能性微流體元件的整合與微型全分析平台建立(1/3) Co-PI 國科會 2012/08/01-2013/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2012 大專生計畫－環境荷爾蒙對卵巢癌之表基因影響之研究 PI 國科會 2012/07/01-2013/02/28
Chan, Michael Wing Yan Department of Biomedical Sciences 2011 表基因沉默之SMAD4標的基因RunX1T1 在卵巢癌中之功能探討及其在卵巢癌病人非侵入性診斷之應用 PI 國科會 2011/08/01-2012/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2010 幽門螺桿菌CagA蛋白在胃癌引起之STAT3活化之對位性基因影響之探討(3/3) PI 國科會 2010/08/01-2011/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2010 泌尿道上皮癌侵犯之分子機轉及其臨床應用之研究 Co-PI 國科會 2010/08/01-2011/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2009 幽門螺桿菌CagA蛋白在胃癌引起之STAT3活化之對位性基因影響之探討(2/3) PI 國科會 2009/08/01-2011/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2008 幽門螺桿菌CagA蛋白在胃癌引起之STAT3活化之對位性基因影響之探討(1/3) PI 國科會 2008/08/01-2011/07/31
Chan, Michael Wing Yan Department of Biomedical Sciences 2007 STAT3 標的基因在胃癌之對位性基因的探討 PI 國科會 2007/11/01-2008/07/31

Patents

Print-friendly
Patents Apply Date Apply Number Patent Number Patent Country Inventor
偵測膀胱癌之新穎表基因生物標記及其方法 2013/10/08 102136274 I496891 R.O.C Michael Chan
Source：Chung Cheng Academic Achievements Information System